Peptide Sequence: GQSCAGEPDE ELVGAFPIFV RNAILGQKQP KRPRSESSCS KDVVRTGFDG LGGRTKFIQP TDTVMIRPLP VKPKTKVKQR VRVKTVPSLF QAKLDTFLWS
TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
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Protein Aliases: E3 ubiquitin-protein ligase TRAIP; RING finger protein 206; TRAF-interacting protein
Gene Aliases: RNF206; SCKL9; TRAIP; TRIP
UniProt ID: (Human) Q9BWF2
Entrez Gene ID: (Human) 10293