Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
FIGURE: 1 / 1
Detects human FCRL2/FcRH2 and FCRL5/FcRH5 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human FCRL1, FCRL3, and FCRL4 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Fc receptor homologs, also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH2 (FCRL2) may have a regulatory role in normal and neoplastic B cell development. FcRH5 (FCRL5) expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FCRL5 may be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. It also may have an immunoregulatory role in marginal zone B-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BXMAS1; CD307b; CD307e; Fc receptor homolog 2; Fc receptor homolog 5; Fc receptor-like 2; Fc receptor-like 5; Fc receptor-like protein 2; Fc receptor-like protein 5; FcR-like protein 2; FcR-like protein 5; FcRH2; FcRH5; IFGP family protein 4; Immune receptor translocation-associated protein 2; immune receptor translocation-associated protein 4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1
Gene Aliases: BXMAS1; CD307; CD307b; CD307e; FCRH2; FCRH5; FCRL2; FCRL5; IFGP4; IRTA2; IRTA4; PRO820; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ503/PRO820; UNQ9236/PRO31998
UniProt ID: (Human) Q96LA5, (Human) Q96RD9
Entrez Gene ID: (Human) 79368, (Human) 83416
Molecular Function: immunoglobulin receptor superfamily
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