GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
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Protein Aliases: alpha 5; GABA(A) receptor subunit alpha-5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; Gamma-aminobutyric acid receptor subunit alpha-5
Gene Aliases: GABRA5
UniProt ID: (Human) P31644
Entrez Gene ID: (Human) 2558