This gene encodes a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
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Protein Aliases: 53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; C1orf10; Cornulin; DRC1; PDRC1; SEP53; Squamous epithelial heat shock protein 53; Tumor-related protein
Gene Aliases: C1orf10; CRNN; DRC1; PDRC1; SEP53
UniProt ID: (Human) Q9UBG3
Entrez Gene ID: (Human) 49860