This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human ILT6/LILRA3.
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD85 antigen-like family member E; CD85e; ILT-6; Immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; Leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; Leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LIR-4; Monocyte inhibitory receptor HM43/HM31
Gene Aliases: CD85E; HM31; HM43; ILT-6; ILT6; LILRA3; LIR-4; LIR4
UniProt ID: (Human) Q8N6C8
Entrez Gene ID: (Human) 11026