Sequence of this protein is as follows: GDLGGYNQYT FSEHSVLDIV NTPNIVVPPE VVAGTEVEVS CMVPDNCPEL RPELSWLGHE GLGEPAVLGR LREDEGTWVQ VSLLHFVPTR
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A; Siglec-4a
Gene Aliases: GMA; MAG; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
UniProt ID: (Human) P20916
Entrez Gene ID: (Human) 4099
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule membrane-bound signaling molecule myelin protein receptor signaling molecule structural protein