Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; LEM domain-containing protein 3
Gene Aliases: LEMD3; MAN1; RGD1561001
UniProt ID: (Human) Q9Y2U8