This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.
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Protein Aliases: Amine oxidase [flavin-containing] A; HGNC:6833; MAO-A; Monoamine oxidase type A; RP1-201D17__B.2
Gene Aliases: MAO-A; MAOA
UniProt ID: (Human) P21397
Entrez Gene ID: (Human) 4128
Molecular Function: oxidase