|Tested species reactivity||Bovine, Human, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified bovine brain MAPs|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1-2 µg/ml|
|Western Blot (WB)||See 1 publications below|
MA5-12813 targets MAP1B/MAP5 in IF and IHC (P) applications and shows reactivity with Bovine, Human, and Rat samples.
The MA5-12813 immunogen is purified bovine brain MAPs.
Microtubule-associated protein 1B (MAP1B, also known as MAP5, MAP1.2, MAP1(x), or MAP1X) is different from MAP1A (also known as MAP1 or MAP1.1). Reportedly, MAP1B/MAP5 is an early MAP; it is present at high levels in embryonic and newborn rat brain and declines several-fold upon brain maturation. In several cellular situations, MAP1B/MAP5 is the first neuronal MAP to appear, and it is found in neurites from their very first emergence from the cell body. Expression of MAP1B/MAP5 is induced by nerve growth factor.
Expression of fragile X mental retardation-1 gene with nuclear export signal mutation changes the expression profiling of mouse cerebella immortal neuronal cell.
MA5-12813 was used in western blot to investigate the role of fragile X mental retardation-1 gene in the pathogenesis of Fragile X syndrome
|Hu L,Chen Y,Evers S,Shen Y||Proteomics (5:3979)||2005|
MAP-1B; microtubule associated protein 1B; microtubule-associated protein 1B; neuraxin; protein phosphatase 1, regulatory subunit 102
BOS_19638; FUTSCH; MAP1B; MAP5; Mtap1b; PPP1R102