|Tested species reactivity||Amphibian, Avian, Bovine, Mouse, Rat, Xenopus|
|Published species reactivity||Mouse, Human, Guinea pig|
|Host / Isotype||Mouse / IgG1|
|Contains||15mM sodium azide|
|Storage Conditions||-20°C or -80°C if preferred|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25044 detects MAP2 from mouse, rat, Xenopus laevis, bovine, quail, and salamander samples.
MA1-25044 has been successfully used in Western blot, immunocytochemistry, and immunofluorescence procedures.
The MA1-25044 immunogen is bovine protein.
MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ABCA1 influences neuroinflammation and neuronal death.
MA1-25044 was used in immunohistochemistry - paraffin section to elucidate the cell-type specific role of ABCA in neuroinflammation in vivo.
|Karasinska JM,de Haan W,Franciosi S,Ruddle P,Fan J,Kruit JK,Stukas S,Lütjohann D,Gutmann DH,Wellington CL,Hayden MR||Neurobiology of disease (54:445)||2013|
Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.
MA1-25044 was used in immunocytochemistry to study retinoic acid-induced gene expression during neuronal differentiation and the role played by elongin A
|Yasukawa T,Bhatt S,Takeuchi T,Kawauchi J,Takahashi H,Tsutsui A,Muraoka T,Inoue M,Tsuda M,Kitajima S,Conaway RC,Conaway JW,Trainor PA,Aso T||Cell reports (2:1129)||2012|
Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.
MA1-25044 was used in immunohistochemistry to study the effect of Gbeta1-deficiency on neural tube and neural progenitor cell proliferation
|Okae H,Iwakura Y||Developmental dynamics : an official publication of the American Association of Anatomists (239:1089)||2010|
Immunolocalization of MAP-2 in routinely formalin-fixed, paraffin-embedded guinea pig brain sections using microwave irradiation: a comparison of different combinations of antibody clones and antigen retrieval buffer solutions.
MA1-25044 was used in immunohistochemistry to study the efficacy of different microwave pre-treatments to restore MAP-2 immunoreactivity in fixed tissue preparations
|Kan RK,Pleva CM,Hamilton TA,Petrali JP||Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada (11:175)||2005|