|Tested species reactivity||Hamster, Human, Mouse, Non-human primate|
|Host / Isotype||Rat / IgG2a|
|Immunogen||The C-terminal part of mouse EB1 (amino acids 125-268)|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1:200 - 1:1000|
|Immunoprecipitation (IP)||2 ug/ml|
|Western Blot (WB)||1:500 - 1:7000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody will not cross-react with mouse EB2 or human EB3.
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.