|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||CHO cells expressing mouse MARCO|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:5-1:10|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Splenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for control.
MA5-16661 was used in flow cytometry to study the role of type 1 Interferons produced by spleen red pulp cells in sensing and controlling malarial infection
|Kim CC,Nelson CS,Wilson EB,Hou B,DeFranco AL,DeRisi JL||PloS one (7:null)||2012|