|Tested species reactivity||Bovine, Human|
|Host / Isotype||Mouse / IgG3|
|Immunogen||Human alveolar macrophages|
|Storage buffer||PBS with 0.1% BSA|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50|
|Immunohistochemistry (Frozen) (IHC (F))||1:50|
|Western Blot (WB)||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-40315 detects MARCO from human and bovine samples.
MA1-40315 has been successfully used in immunohistochemistry (frozen), immunofluorescence, immunoprecipitation, western blot, and flow cytometry applications.
The MA1-40315 immunogen is human alveolar macrophages.
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.