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|Tested species reactivity||Bovine, Human|
|Host / Isotype||Mouse / IgG3|
|Immunogen||Human alveolar macrophages|
|Storage buffer||PBS with 0.1% BSA|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50|
|Immunohistochemistry (Frozen) (IHC (F))||1:50|
|Western Blot (WB)||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-40315 detects MARCO from human and bovine samples.
MA1-40315 has been successfully used in immunohistochemistry (frozen), immunofluorescence, immunoprecipitation, western blot, and flow cytometry applications.
The MA1-40315 immunogen is human alveolar macrophages.
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
SCARA2; scavenger receptor class A, member 2