MA5-17118 targets MARK3 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17118 immunogen is purified recombinant fragment of human MARK3 (amino acids: 435-658) expressed in E. Coli.
MA5-17118 detects MARK3 which has a predicted molecular weight of approximately 87kDa.
The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: C-TAK1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; EMK2/MARK3 serine-threonine protein kinase; MAP/microtubule affinity-regulating kinase 3; MPK-10; Par-1a; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
Gene Aliases: 1600015G02Rik; A430080F22Rik; C-TAK1; CTAK1; EMK2; ETK-1; ETK1; KP78; MARK3; MPK10; Par-1a; PAR1A