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|Tested species reactivity||Human|
|Published species reactivity||Mouse, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant MART-1 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100 - 200|
|Western Blot (WB)||1 µg/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-14168 targets MART-1 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-14168 immunogen is recombinant MART-1 protein.
MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. MART-1 is present in melanosomes and endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.
MA5-14168 was used in western blot to determine which HDAC to target to specifically inhibit metastatic melanoma
|Woan KV,Lienlaf M,Perez-Villaroel P,Lee C,Cheng F,Knox T,Woods DM,Barrios K,Powers J,Sahakian E,Wang HW,Canales J,Marante D,Smalley KS,Bergman J,Seto E,Kozikowski A,Pinilla-Ibarz J,Sarnaik A,Celis E,Weber J,Sotomayor EM,Villagra A||Molecular oncology (9:1447)||2015|
Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.
MA5-14168 was used in western blot to study the behavior and functional abilities of melanocytes expressing MC1R red hair color variants
|Roberts DW,Newton RA,Leonard JH,Sturm RA||Journal of cellular physiology (215:344)||2008|
Loss of BRM expression is a frequently observed event in poorly differentiated clear cell renal cell carcinoma.
MA5-14168 was used in immunohistochemistry to study the incidence of BRM expression loss in patients with poorly differentiated clear cell renal cell carcinoma
|Xia QY,Rao Q,Cheng L,Shen Q,Shi SS,Li L,Liu B,Zhang J,Wang YF,Shi QL,Wang JD,Ma HH,Lu ZF,Yu B,Zhang RS,Zhou XJ||Histopathology (64:847)||2014|
Renal cell carcinomas with t(6;11)(p21;q12) presenting with tubulocystic renal cell carcinoma-like features.
MA5-14168 was used in immunohistochemistry to report on a case of renal cell carcinoma with t(6;11)(p21;q12
|Rao Q,Zhang XM,Tu P,Xia QY,Shen Q,Zhou XJ,Shi QL||International journal of clinical and experimental pathology (6:1452)||2013|
Cathepsin K expression in a wide spectrum of perivascular epithelioid cell neoplasms (PEComas): a clinicopathological study emphasizing extrarenal PEComas.
MA5-14168 was used in immunohistochemistry to study the expression and diagnostic value of cathepsin K expression in a wide range of extra-renal perivascular epithelioid cell neoplasms
|Rao Q,Cheng L,Xia QY,Liu B,Li L,Shi QL,Shi SS,Yu B,Zhang RS,Ma HH,Lu ZF,Tu P,Zhou XJ||Histopathology (62:642)||2013|
Expression of E-cadherin in angiomyolipoma.
MA5-14168 was used in immunohistochemistry to perform a systematic study of E-cadherin expression in angiomyolipoma
|Wang Z,Gong Q,Fan Q||Human pathology (43:2348)||2012|
Renal cell carcinomas with t(6;11)(p21;q12): A clinicopathologic study emphasizing unusual morphology, novel alpha-TFEB gene fusion point, immunobiomarkers, and ultrastructural features, as well as detection of the gene fusion by fluorescence in situ hybridization.
MA5-14168 was used in immunohistochemistry to perform a detailed clinicopathological study of renal cell carcinomas with t(6;11)(p21;q12)
|Rao Q,Liu B,Cheng L,Zhu Y,Shi QL,Wu B,Jiang SJ,Wang Y,Wang X,Yu B,Zhang RS,Ma HH,Lu ZF,Tu P,Wang JD,Zhou XJ||The American journal of surgical pathology (36:1327)||2012|
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
MA5-14168 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
|Yin WH,Li J,Chan JK||Diagnostic pathology (7:null)||2012|
Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm.
MA5-14168 was used in immunohistochemistry to report a clinical case of microscopic lymphangioleiomyomatosis perivascular epithelioid cell neoplasm in uterus
|Clay MR,Gibson P,Lowell J,Cooper K||International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists (30:71)||2011|
Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract.
MA5-14168 was used in immunohistochemistry to investigate the polypoid PEComa in the gastrointestinal tract
|Ryan P,Nguyen VH,Gholoum S,Carpineta L,Abish S,Ahmed NN,Laberge JM,Riddell RH||The American journal of surgical pathology (33:475)||2009|
Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimens.
MA5-14168 was used in immunohistochemistry to review the diagnostic difficulty of metastatic spindle cell melanoma
|Piao Y,Guo M,Gong Y||Cancer (114:94)||2008|
Hyperpigmentation during interferon-alpha therapy for chronic hepatitis C virus infection.
MA5-14168 was used in immunohistochemistry to study melanin deposition during interferon-alpha therapy for HCV infection
|Willems M,Munte K,Vrolijk JM,Den Hollander JC,Böhm M,Kemmeren MH,De Man RA,Brouwer JT||The British journal of dermatology (149:390)||2003|
Acral lentiginous melanoma: an immunohistochemical study of 20 cases.
MA5-14168 was used in immunohistochemistry to identify the diagnostic markers for acral lentiginous melanoma
|Kim YC,Lee MG,Choe SW,Lee MC,Chung HG,Cho SH||International journal of dermatology (42:123)||2003|
Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations.
MA5-14168 was used in immunohistochemistry to study 5 antibodies as diagnostic markers of melanoma incytologic preparation
|Sheffield MV,Yee H,Dorvault CC,Weilbaecher KN,Eltoum IA,Siegal GP,Fisher DE,Chhieng DC||American journal of clinical pathology (118:930)||2002|
antigen LB39-AA; antigen SK29-AA; melanoma antigen recognized by T-cells 1; protein Melan-A
MART-1; MART1; MLANA