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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human protein (within residues 100-200).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is not recommended for ICC/IF applications.
Suggested positive control: antigen standard for SERPINB5 (transient overexpression lysate), HeLa whole cell extract.
Maspin is an extracellular matrix tumor supressor that blocks the growth, invasion, and metastatic properties of mammary and prostate tumors. Structurally Maspin is a serine protease inhibitor (Serpin), but it does not undergo the stressed to relaxed conformational transition characteristic of active serpins and exhibits no serine protease inhibitory activity.
Maspin is also expressed by the corneal epithelium and regulates migration and adhesion of corneal stromal fibroblasts and myofibroblasts during corneal wound healing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
clade B (ovalbumin); maspin; member 5; peptidase inhibitor 5; PI-5; PI5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serpin B5; serpin peptidase inhibitor, clade B (ovalbumin), member 5
maspin; PI5; SERPINB5