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This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
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Protein Aliases: greatwall kinase homolog; greatwall protein kinase; GW; hGWL; MAST-L; Microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall
Gene Aliases: GREATWALL; GW; GWL; MAST-L; MASTL; THC2
UniProt ID: (Human) Q96GX5
Entrez Gene ID: (Human) 84930
Molecular Function:
annexin
calcium-binding protein
calmodulin
intracellular calcium-sensing protein
kinase
non-receptor serine/threonine protein kinase
protein kinase
transfer/carrier protein
transferase
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