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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
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Protein Aliases: cell devision cycle-like 1; cyclin-like 1; DNA replication licensing factor MCM2; MGC10606; minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance protein 2 homolog; Nuclear protein BM28
Gene Aliases: BM28; CCNL1; cdc19; CDCL1; D3S3194; DFNA70; KIAA0030; MCM2; MITOTIN
UniProt ID: (Human) P49736
Entrez Gene ID: (Human) 4171
Molecular Function: DNA metabolism protein