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Alomone Labs, LTD
MCT1 (SLC16A1) (extracellular) Polyclonal Antibody, APC
FIGURE: 1 / 2
MCT1 (SLC16A1) (extracellular) Antibody (AMT-011-APC50UL) in Flow
Cell surface detection of monocarboxylate transporter 1 by direct flow cytometry in live intact human Jurkat T-cell leukemia cells: - (black line) cells. (red) Cells + Rabbit IgG Isotype control-APC (#RIC-001-APC). (green) Cells + Anti-MCT1 (SLC16A1) (extracellular)-APC Antibody (#AMT-011-APC), (5 µg).
Product Details
AMT-011-APC50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)GRLNDMYGDYKYT, corresponding to amino acid residues 403-415 of rat MCT1, Extracellular, 6th loop
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ36745; MCT 1; MGC44475; monocarboxylate transporter; Monocarboxylate transporter 1; SLC16A1 protein; solute carrier 16 (monocarboxylic acid transporter), member 1; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Gene Aliases: AL022710; HHF7; MCT; MCT1; MCT1D; RATMCT1; RNMCT1; SLC16A1
UniProt ID: (Human) P53985, (Rat) P53987, (Mouse) P53986
Entrez Gene ID: (Human) 6566, (Rat) 25027, (Mouse) 20501
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
mevalonate transmembrane transporter activity
symporter activity
protein homodimerization activity
organic cyclic compound binding
protein binding
secondary active monocarboxylate transmembrane transporter activity
transporter
pyruvate metabolic process
lipid metabolic process
monocarboxylic acid transport
mevalonate transport
response to food
plasma membrane lactate transport
glucose homeostasis
regulation of insulin secretion
leukocyte migration
centrosome organization
behavioral response to nutrient
cellular response to organic cyclic compound
lactate transmembrane transport
transport
transmembrane transport
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