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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MED12L Antibodies

          Proteintech

          MED12L Recombinant Rabbit Monoclonal Antibody (240101C11), CoraLite® Plus 488

          View all (5) MED12L antibodies

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          Cite MED12L Recombinant Rabbit Monoclonal Antibody (240101C11), CoraLite® Plus 488

          • Antibody Testing Data (1)
          MED12L Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          MED12L Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MED12L Antibody (CL488-83540) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CoraLite® Plus 488 MED12L antibody (CL488-83540, Clone: 240101C11) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MED12L Antibody in Immunocytochemistry (ICC/IF)
          MED12L Recombinant Rabbit Monoclonal Antibody (240101C11), CoraLite® Plus 488

          Product Details

          CL488-83540

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          240101C11

          Immunogen

          MED12L fusion protein Ag34636
          View immunogen

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: LSVTASTRPR SPVGENADEH YSKDHDVKME IFSPMPGESC ENANTSLGRR MSVNCEKLVK REKPRELIFP SNYDLLRHLQ

          Target Information

          MED12L, also named as KIAA1635, TNRC11L, TRALP and TRALPUSH, belongs to the Mediator complex subunit 12 family. MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED12L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED12L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: mediator complex subunit 12-like; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; mediator of RNA polymerase II transcription, subunit 12 homolog-like; no opposite paired repeat protein; Thyroid hormone receptor-associated-like protein; Trinucleotide repeat-containing gene 11 protein-like

          View more View less

          Gene Aliases: KIAA1635; MED12L; NOPAR; PRO0314; TNRC11L; TRALP; TRALPUSH

          View more View less

          UniProt ID: (Human) Q86YW9

          View more View less

          Entrez Gene ID: (Human) 116931

          View more View less

          Function(s)
          RNA polymerase II transcription coactivator activity beta-catenin binding general transcription factor
          Process(es)
          transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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