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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody will cross-react with mouse and rat MEK2, based on sequence homology.
Suggested positive control: 293 whole cell lysate.
MEK2 (MAP kinase kinase/ERK kinase 2) is activated through phosphorylation of its serine residues at positions 217 and 221 by a variety of cytokines and growth factors. It is responsible for the phosphorylation/activation of MAP kinases and ERKs, and is an essential component in the transduction of mitogenic signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ERK activator kinase 2; ERK kinase 2; MAP kinase kinase 2; MAPK; MAPK/ERK kinase 2; mitogen-activated protein kinase kinase 2, p45
CFC4; MAP2K2; MAPKK2; MEK2; MKK2; PRKMK2