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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human MAP3K2 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||1/200 - 1/1000|
|Immunofluorescence (IF)||1:200 - 1:1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15908 targets MAP3K2 in ICC, IF and WB applications and shows reactivity with Human samples.
The MA5-15908 immunogen is purified recombinant fragment of human MAP3K2 expressed in E. Coli. .
MA5-15908 detects MAP3K2 which has a predicted molecular weight of approximately 70kDa.
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MAP/ERK kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MEKK2, MEKK2B, MAP/ERK kinase kinase 2; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b
9630061B06Rik; AI585793; MAP3K2; MAPKKK2; MEKK2; MEKK2B