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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids surrounding pSer225 of human MEP50|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
It is not recommended to aliquot this antibody.
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
androgen receptor cofactor p44; methylosome protein 50; OTTHUMP00000013473; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50; WD45; WDR77