MA5-15358 targets MER in WB applications and shows reactivity with Human samples.
The MA5-15358 immunogen is purified recombinant fragment of MER expressed in E. Coli.
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa .
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Protein Aliases: c-mer; c-mer proto-oncogene tyrosine kinase; MER; MER receptor tyrosine kinase; MERTK; MGC133349; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; RP38; STK kinase; Tyrosine-protein kinase Mer
Gene Aliases: c-Eyk; c-mer; MER; MERTK; RP38; Tyro12
UniProt ID: (Human) Q12866
Entrez Gene ID: (Human) 10461