Sequence of this protein is as follows: MAQPLCPPLS ESWMLSAAWG PTRRPPPSDK DCGRSLVSSP DSWGSTPADS PVASPARPGT LRD
Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis.
Protein Aliases: bHLHc5; Class C basic helix-loop-helix protein 5; mesoderm posterior 1 homolog; mesoderm posterior basic helix-loop-helix transcription factor 1; Mesoderm posterior protein 1; MGC10676
Gene Aliases: BHLHC5; MESP1
UniProt ID: (Human) Q9BRJ9
Entrez Gene ID: (Human) 55897