Immunofluorescent analysis of METTL11A/NTM1A showing staining in the nucleus of Raji cells. Raji cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a METTL11A/NTM1A polyclonal antibody (Product # PA5-35925) diluted at 1:500. Blue: Hoechst 33342 staining.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 199 of METTL11A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200). [supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.