Proteintech

METTL4 Polyclonal Antibody

View all (7) METTL4 antibodies

Questions & Answers

Questions & Answers

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METTL4 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 17718-1-AP (METTL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

METTL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human testis using 17718-1-AP (METTL4 antibody) at dilution of 1:100 (under 40x lens).

METTL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human testis using 17718-1-AP (METTL4 antibody) at dilution of 1:100 (under 10x lens).

METTL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human skin using 17718-1-AP (METTL4 antibody) at dilution of 1:100 (under 40x lens).

METTL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human skin using 17718-1-AP (METTL4 antibody) at dilution of 1:100 (under 10x lens).

METTL4 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 17718-1-AP (METTL4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

METTL4 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 17718-1-AP (METTL4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

17718-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:4,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	METTL4 Fusion Protein Ag12093 (125-472 aa encoded by BC111020) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.25 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: ISISIIGKK RKRCVVFNQG ELDAMEYHTK IRELILDGSL QLIQEGLKSG FLYPLFEKQD KGSKPITLPL DACSLSELCE MAKHLPSLNE MEHQTLQLVE EDTSVTEQDL FLRVVENNSS FTKVITLMGQ KYLLPPKSSF LLSDISCMQP LLNYRKTFDV IVIDPPWQNK SVKRSNRYSY LSPLQIKQIP IPKLAAPNCL LVTWVTNRQK HLRFIKEELY PSWSVEVVAE WHWVKITNSG EFVFPLDSPH KKPYEGLILG RVQEKTALPL RNADVNVLPI PDHKLIVSVP CTLHSHKPPL AEVLKDYIKP DGEYLELFAR NLQPGWTSWG NEVLKFQHVD YFIALESGS (125-472 aa encoded by BC111020)

Target Information

METTL4 gene ontology annotations related to this gene include methyltransferase activity; nucleic acid binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Methyltransferase-like protein 4; N(6)-adenine-specific DNA methyltransferase METTL4; N(6)-adenine-specific methyltransferase METTL4; snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4

Gene Aliases: 2410198H06Rik; A730091E08Rik; AV296509; HsT661; METTL4; RGD1306451

UniProt ID: (Human) Q8N3J2, (Mouse) Q3U034

Entrez Gene ID: (Human) 64863, (Mouse) 76781, (Rat) 316731

Molecular Function: RNA metabolism protein RNA methyltransferase nucleic acid metabolism protein

DNA methylation on adenine nucleobase-containing compound metabolic process biological_process methylation

Process(es)

nucleic acid binding site-specific DNA-methyltransferase (adenine-specific) activity rRNA (adenine-N6,N6-)-dimethyltransferase activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity