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METTL7A Antibody (TA809878) in IHC (P)
Immunohistochemical staining of paraffin-embedded human lymph node tissue within the normal limits using anti-METTL7A mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809878)(1:2000).
Product Details
TA809878
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI4B10
Immunogen
Human recombinant protein fragment corresponding to amino acids 34-104 of human METTL7A produced in E.coli.
Conjugate
Form
liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Methyltransferase-like protein 7A; N6-adenosine-methyltransferase TMT1A; Protein AAM-B; Thiol methyltransferase 1A; Thiol S-methyltransferase TMT1A
Gene Aliases: AAM-B; METTL7A; PRO0066; TMT1A; UNQ1902/PRO4348
UniProt ID: (Human) Q9H8H3
Entrez Gene ID: (Human) 25840
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