MA5-13556 targets Human Milk Fat Globule 1 in IF, IHC (P), IP, and WB applications and shows reactivity with Human samples.
The MA5-13556 immunogen is delipidated human milk fat globule membrane preparation.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
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Protein Aliases: Breast epithelial antigen BA46; HMFG; Lactadherin; Lactadherin short form; Medin; MFG-E8; MFGM; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; O-acetyl disialoganglioside synthase; SED1; sperm associated antigen 10; sperm surface protein hP47
Gene Aliases: BA46; EDIL1; HMFG; hP47; HsT19888; MFG-E8; MFGE8; MFGM; OAcGD3S; SED1; SPAG10
UniProt ID: (Human) Q08431
Entrez Gene ID: (Human) 4240
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter