|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MFRN2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MFRN2 is mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hMRS3/4; MFRN2; Mitochondrial iron transporter 2; mitochondrial RNA splicing protein 3/4; Mitochondrial RNA-splicing protein 3/4 homolog; mitoferrin 2; Mitoferrin-2; MRS3/4; MRS4L; putative mitochondrial solute carrier; solute carrier family 25 (mitochondrial iron transporter), member 28; Solute carrier family 25 member 28; solute carrier family 25, member 28
Gene Aliases: MFRN2; MRS3/4; MRS4L; NPD016; SLC25A28
UniProt ID: (Human) Q96A46
Entrez Gene ID: (Human) 81894
Molecular Function: RNA binding protein amino acid transporter calcium-binding protein calmodulin intracellular calcium-sensing protein mitochondrial carrier protein nucleic acid binding ribosomal protein transfer/carrier protein transporter
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