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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MFRN2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MFRN2 is mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
hMRS3/4; MFRN2; mitochondrial iron transporter 2; mitochondrial RNA splicing protein 3/4; mitochondrial RNA-splicing protein 3/4 homolog; mitoferrin 2; mitoferrin-2; MRS3/4; MRS4L; putative mitochondrial solute carrier; solute carrier family 25 (mitochondrial iron transporter), member 28; solute carrier family 25, member 28
MFRN2; MRS3/4; MRS4L; NPD016; SLC25A28