Product References
The effect of diet and exercise on tobacco carcinogen-induced lung cancer.
Carcinogenesis
Elisia I,Cho B,Hay M,Li MY,Hofs E,Lam V,Dyer RA,Lum J,Krystal G
MA5-13506 was used in Western Blotting to study the role of different types and levels of low carbohydrate, protein and lipid in lung cancer induced by tobacco-specific nicotine derived nitrosamine ketone.
Tue May 14 00:00:00 EDT 2019
Inhibition of Human Adrenocortical Cancer Cell Growth by Temozolomide in Vitro and the Role of the MGMT Gene.
The Journal of clinical endocrinology and metabolism
Creemers SG,van Koetsveld PM,van den Dungen ES,Korpershoek E,van Kemenade FJ,Franssen GJ,de Herder WW,Feelders RA,Hofland LJ
MA513506 was used in immunohistochemistry - paraffin section to discuss therapeutic options available for patients with adrenocortical carcinomas
Thu Dec 01 00:00:00 EST 2016
Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Virchows Archiv : an international journal of pathology
Boissière-Michot F,Frugier H,Ho-Pun-Cheung A,Lopez-Crapez E,Duffour J,Bibeau F
MA513506 was used in immunohistochemistry to identify immunohistological features that distinguish hereditary colorectal cancer from spontaneous cases
Mon Aug 01 00:00:00 EDT 2016
Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
Cancer medicine
Nitta Y,Shimizu S,Shishido-Hara Y,Suzuki K,Shiokawa Y,Nagane M
MA5-13506 was used in western blot to discover enhancment of temozolomide-induced growth suppression of mutant EFGR in glioma cells in vivo by nimotuzumab
Tue Mar 01 00:00:00 EST 2016
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
Molecular cancer therapeutics
Ramirez YP,Mladek AC,Phillips RM,Gynther M,Rautio J,Ross AH,Wheelhouse RT,Sakaria JN
MA5-13506 was used in western blot to report the effects of new temozolomide analogues on glioblastoma multiforme
Thu Jan 01 00:00:00 EST 2015
The prognostic impact of MGMT expression on low-grade gangliogliomas: a clinicopathological and immunohistochemical study.
Folia neuropathologica
Chang IW,Hsu CT,Lin JW,Hung CH
MA5-13506 was used in immunohistochemistry to study the prognostic value of the immunohistochemical expression of MGMT in low-grade ganglioglioma
Mon Jul 14 00:00:00 EDT 2014
Correlation of histomorphologic prognostic markers and proliferative index with loss of heterozygosity 1p/19q and MGMT status in diffusely infiltrating gliomas.
Medical journal, Armed Forces India
Deb P,Mani NS,Sudumbrekar SM,Taneja N,Patrikar S
MA5-13506 was used in immunohistochemistry to study the prognostic and diagnostic value of 1p/19q loss of heterozygosity and MGMT expression in diffusely infiltrating gliomas
Mon Jul 01 00:00:00 EDT 2013
Infratentorial low-grade oligoastrocytoma with aggressive clinical behavior in an adult: a case report with genetic characterization.
Brain tumor pathology
Sano K,Toda M,Sasaki H,Kitamura Y,Mikami S,Hirato J,Inoue S,Kawase T,Yoshida K
MA5-13506 was used in immunohistochemistry to report on a case of clinically aggressive infratentorial low-grade oligoastrocytoma
Mon Apr 01 00:00:00 EDT 2013
Exclusion of histiocytes/endothelial cells and using endothelial cells as internal reference are crucial for interpretation of MGMT immunohistochemistry in glioblastoma.
The American journal of surgical pathology
Hsu CY,Lin SC,Ho HL,Chang-Chien YC,Hsu SP,Yen YS,Chen MH,Guo WY,Ho DM
MA5-13506 was used in immunohistochemistry to study the predictive value of MGMT protein expression and promoter methylation in glioblastoma patients receiving temozolomide and the use of endothelial cells as an internal reference
Fri Feb 01 00:00:00 EST 2013
Clinicopathological features of human brainstem gliomas.
Brain tumor pathology
Oka H,Utsuki S,Tanizaki Y,Hagiwara H,Miyajima Y,Sato K,Kusumi M,Kijima C,Fujii K
MA5-13506 was used in immunohistochemistry to report on the clinical and pathological features of 25 cases of human brain stem glioma
Tue Jan 01 00:00:00 EST 2013
The Changes in MGMT Promoter Methylation Status in Initial and Recurrent Glioblastomas.
Translational oncology
Park CK,Kim JE,Kim JY,Song SW,Kim JW,Choi SH,Kim TM,Lee SH,Kim IH,Park SH
MA5-13506 was used in immunohistochemistry to study the role of reduced methylation of the MGMT promoter in the acquired resistance to temozolomide of glioblastomas
Mon Oct 01 00:00:00 EDT 2012
Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors.
Journal of neuro-oncology
Takano S,Kato Y,Yamamoto T,Kaneko MK,Ishikawa E,Tsujimoto Y,Matsuda M,Nakai K,Yanagiya R,Morita S,Tsuboi K,Matsumura A
MA5-13506 was used in immunohistochemistry to study the prognostic value of IDH1 mutation, p53 and internexin in glial tumors
Sun Jul 01 00:00:00 EDT 2012
MGMT promoter hypermethylation and its associations with genetic alterations in a series of 350 brain tumors.
Journal of neuro-oncology
Mellai M,Monzeglio O,Piazzi A,Caldera V,Annovazzi L,Cassoni P,Valente G,Cordera S,Mocellini C,Schiffer D
MA5-13506 was used in western blot to investigate the prognostic significance of MGMT promoter hypermethylation in brain tumors
Tue May 01 00:00:00 EDT 2012
The prognostic impact of O6-methylguanine DNA methyltransferase and epidermal growth factor receptor expressions on primary gliosarcoma: a clinicopathologic and immunohistochemical study of seven cases at a single institution.
Indian journal of pathology & microbiology
Lin JW,Wu YT,Chang IW
MA5-13506 was used in immunohistochemistry to study the prognostic value of MGMT and EGFR expression in primary gliosarcoma
Thu Apr 12 00:00:00 EDT 2012
Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma.
Clinics (Sao Paulo, Brazil)
Uno M,Oba-Shinjo SM,Camargo AA,Moura RP,Aguiar PH,Cabrera HN,Begnami M,Rosemberg S,Teixeira MJ,Marie SK
MA5-13506 was used in immunohistochemistry - paraffin section to study methylation of the O6-methylguanine-DNA-methyltransferase promoter in patients with glioblastoma
Wed Feb 22 00:00:00 EST 2012
O-6-methylguanine-DNA methyltransferase (MGMT) immunohistochemical expression in pituitary corticotroph adenomas.
Neurosurgery
Salehi F,Scheithauer BW,Kovacs K,Horvath E,Syro LV,Sharma S,Manoranjan B,Cusimano M
MA5-13506 was used in immunohistochemistry to study the immunohistochemical expression of O-6-methylguanine-DNA methyltransferase in pituitary corticotroph adenomas
Wed Feb 01 00:00:00 EST 2012
The status of MGMT protein expression is a prognostic factor for meningeal hemangiopericytoma: a clinicopathologic and immunohistochemical study of 12 cases at a single institution.
Journal of neuro-oncology
Chang IW,Lin JW,Wu YT
MA5-13506 was used in immunohistochemistry to study the prognostic value of O6-methylguanine-DNA methyltransferase in meningeal hemangiopericytoma
Thu Dec 01 00:00:00 EST 2011
Evaluation of O6-methylguanine-DNA methyltransferase by immunohistochemistry: best clinical and research practices.
Pathology, research and practice
Neto JC,Carvalho K,Olivieri E,Carraro D,Cunha I,Vassallo J,Kagohara L,Soares F,Rocha R
MA5-13506 was used in immunohistochemistry to study the best practices for the immunohistochemical measurement of MGMT in invasive breast carcinoma
Mon Aug 15 00:00:00 EDT 2011
Differential hypermethylation of genes in vulvar cancer and lichen sclerosus coexisting or not with vulvar cancer.
International journal of cancer
Guerrero D,Guarch R,Ojer A,Casas JM,Méndez-Meca C,Esteller M,Barba-Ramos E,Garcia-Bragado F,Puras A
MA5-13506 was used in immunohistochemistry to investigate the changes of gene promoter methylation in specific types of vulvar cancer and lichen sclerosus
Wed Jun 15 00:00:00 EDT 2011
Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
Journal of neuro-oncology
Faoro D,von Bueren AO,Shalaby T,Sciuscio D,Hürlimann ML,Arnold L,Gerber NU,Haybaeck J,Mittelbronn M,Rutkowski S,Hegi M,Grotzer MA
MA5-13506 was used in western blot to investigate MGMT status in childhood medulloblastomas and MB/PNET cell lines
Sun May 01 00:00:00 EDT 2011
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing.
Brain tumor pathology
Takano S,Tian W,Matsuda M,Yamamoto T,Ishikawa E,Kaneko MK,Yamazaki K,Kato Y,Matsumura A
MA5-13506 was used in immunohistochemistry to investigate the distribution of IDH1 mutation in human gliomas
Fri Apr 01 00:00:00 EDT 2011
Quantitative digital assessment of MGMT immunohistochemical expression in glioblastoma tissue.
Brain tumor pathology
Araki Y,Mizoguchi M,Yoshimoto K,Shono T,Amano T,Nakamizo A,Suzuki SO,Iwaki T,Sasaki T
MA5-13506 was used in immunohistochemistry to investigate the expression of MGMT in glioblastoma tissue
Tue Feb 01 00:00:00 EST 2011
Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.
Neuro-oncology
Park CK,Kim J,Yim SY,Lee AR,Han JH,Kim CY,Park SH,Kim TM,Lee SH,Choi SH,Kim SK,Kim DG,Jung HW
MA5-13506 was used in immunohistochemistry to study the value of methylation-specific multiplex ligation probe amplification for measuring pseudoprogression in glioblastoma patients
Tue Feb 01 00:00:00 EST 2011
O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.
BMC cancer
Brell M,Ibáñez J,Tortosa A
MA5-13506 was used in immunohistochemistry to review methods to analyze O6-Methylguanine-DNA methyltransferase
Wed Jan 26 00:00:00 EST 2011
Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report.
Neurologia medico-chirurgica
Tanaka H,Sasayama T,Nishihara M,Arai A,Kawamura A,Kanomata N,Itoh T,Kohmura E
MA5-13506 was used in immunohistochemistry to investigate the effect of temozolomide on sarcoma treatment in one patient
Wed Jan 05 00:00:00 EST 2011
Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers.
Gut
Svrcek M,Buhard O,Colas C,Coulet F,Dumont S,Massaoudi I,Lamri A,Hamelin R,Cosnes J,Oliveira C,Seruca R,Gaub MP,Legrain M,Collura A,Lascols O,Tiret E,Fléjou JF,Duval A
MA5-13506 was used in immunohistochemistry to study methylation tolerance due to a MGMT field defect and its role in colorectal cancers
Mon Nov 01 00:00:00 EDT 2010
O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
Lung cancer (Amsterdam, Netherlands)
Wu PF,Kuo KT,Kuo LT,Lin YT,Lee WC,Lu YS,Yang CH,Wu RM,Tu YK,Tasi JC,Tseng HM,Tseng SH,Cheng AL,Lin CH
MA5-13506 was used in immunohistochemistry to investigate the role of O(6)-methylguanine-DNA methyltransferase on lung cancer metastases
Tue Jun 01 00:00:00 EDT 2010
Loss expression of O6-methylguanine DNA methyltransferase by promoter hypermethylation and its relationship to betel quid chewing in oral squamous cell carcinoma.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Huang SH,Lee HS,Mar K,Ji DD,Huang MS,Hsia KT
MA5-13506 was used in immunohistochemistry to investigate the effect of O6-methylguanine DNA methyltransferas on oral carcinogenesis progression
Tue Jun 01 00:00:00 EDT 2010
MGMT promoter hypermethylation in a series of 104 glioblastomas.
Cancer genomics & proteomics
Mellai M,Caldera V,Annovazzi L,Chiò A,Lanotte M,Cassoni P,Finocchiaro G,Schiffer D
MA5-13506 was used in western blot to investigate the methylation status of MGMT promoter in glioblastomas
Wed Dec 30 00:00:00 EST 2009
MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yip S,Miao J,Cahill DP,Iafrate AJ,Aldape K,Nutt CL,Louis DN
MA5-13506 was used in western blot to investigate the occurrence of MSH6 mutations in glioblastomas during temozolomide therapy and the developmend of temozolomide resistance
Wed Jul 15 00:00:00 EDT 2009
Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations.
Human pathology
Kim JI,Suh JT,Choi KU,Kang HJ,Shin DH,Lee IS,Moon TY,Kim WT
MA5-13506 was used in immunohistochemistry to investigate the status of O(6)-methylguanine-DNA methyltransferase protein and its promoter hypermethylation in soft tissue sarcomas
Wed Jul 01 00:00:00 EDT 2009
Correlation among pathology, genetic and epigenetic profiles, and clinical outcome in oligodendroglial tumors.
International journal of cancer
Kuo LT,Kuo KT,Lee MJ,Wei CC,Scaravilli F,Tsai JC,Tseng HM,Kuo MF,Tu YK
MA5-13506 was used in immunohistochemistry to study the correlation of pathology, genetic and epigenetic profiles with clinical outcome in oligodendroglial tumors
Mon Jun 15 00:00:00 EDT 2009
O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kulke MH,Hornick JL,Frauenhoffer C,Hooshmand S,Ryan DP,Enzinger PC,Meyerhardt JA,Clark JW,Stuart K,Fuchs CS,Redston MS
MA5-13506 was used in immunohistochemistry to examine the effect of
Thu Jan 01 00:00:00 EST 2009
Prospective trial of gross-total resection with Gliadel wafers followed by early postoperative Gamma Knife radiosurgery and conformal fractionated radiotherapy as the initial treatment for patients with radiographically suspected, newly diagnosed glioblastoma multiforme.
Journal of neurosurgery
Smith KA,Ashby LS,Gonzalez LF,Gonzalez F,Brachman DG,Thomas T,Coons SW,Battaglia M,Scheck A
MA5-13506 was used in immunohistochemistry to evaluate the therapeutic efficacy of a treatment regimen for glioblastoma multiformes
Mon Dec 01 00:00:00 EST 2008
IFN-beta sensitizes neuroblastoma to the antitumor activity of temozolomide by modulating O6-methylguanine DNA methyltransferase expression.
Molecular cancer therapeutics
Rosati SF,Williams RF,Nunnally LC,McGee MC,Sims TL,Tracey L,Zhou J,Fan M,Ng CY,Nathwani AC,Stewart CF,Pfeffer LM,Davidoff AM
MA5-13506 was used in western blot to examine the effect of IFN-beta on the antitumor activity of temozolomide
Mon Dec 01 00:00:00 EST 2008
Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.
Brain pathology (Zurich, Switzerland)
Preusser M,Charles Janzer R,Felsberg J,Reifenberger G,Hamou MF,Diserens AC,Stupp R,Gorlia T,Marosi C,Heinzl H,Hainfellner JA,Hegi M
MA5-13506 was used in immunohistochemistry to investigate the prognostic significance of MGMT in glioblastoma multiforme patients
Wed Oct 01 00:00:00 EDT 2008
Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma.
International journal of cancer
Voelter V,Diserens AC,Moulin A,Nagel G,Yan P,Migliavacca E,Rimoldi D,Hamou MF,Kaina B,Leyvraz S,Hegi ME
MA5-13506 was used in immunohistochemistry to study whether the DNA-repair protein MGMT may be involved in the variability of response to chemotherapy in uveal melanoma
Mon Sep 01 00:00:00 EDT 2008
Aberrant crypt foci in the adenoma prevention with celecoxib trial.
Cancer prevention research (Philadelphia, Pa.)
Cho NL,Redston M,Zauber AG,Carothers AM,Hornick J,Wilton A,Sontag S,Nishioka N,Giardiello FM,Saltzman JR,Gostout C,Eagle CJ,Hawk ET,Bertagnolli MM
MA5-13506 was used in immunohistochemistry to study aberrant crypt foci as a potential surrugate end-point biomarker in an adenoma prevention with celecoxib trial
Sun Jun 01 00:00:00 EDT 2008
Prognostic significance of loss of O6-methylguanine-DNA methyltransferase expression in supratentorial diffuse low-grade astrocytoma.
Surgical neurology
Nakasu S,Fukami T,Jito J,Matsuda M
MA5-13506 was used in immunohistochemistry to study the prognostic significance of loss of MGMT expression in supratentorial diffuse low-grade astrocytoma
Sat Dec 01 00:00:00 EST 2007
Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide.
Japanese journal of clinical oncology
Nagane M,Kobayashi K,Ohnishi A,Shimizu S,Shiokawa Y
MA5-13506 was used in western blot to investigate the efficacy of temozolomide treatment against recurrent glioblastoma and the prognostic value of O6-methylguanine-DNA methyltransferase protein expression for this treatment
Sat Dec 01 00:00:00 EST 2007
Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Gut
Ogino S,Kawasaki T,Kirkner GJ,Suemoto Y,Meyerhardt JA,Fuchs CS
MA5-13506 was used in immunohistochemistry to investigate the epigenetic phenotype of colorectal cancer
Thu Nov 01 00:00:00 EDT 2007
Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.
Clinical cancer research : an official journal of the American Association for Cancer Research
Sánchez-de-Abajo A,de la Hoya M,van Puijenbroek M,Tosar A,López-Asenjo JA,Díaz-Rubio E,Morreau H,Caldes T
MA5-13506 was used in immunohistochemistry to study colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer
Mon Oct 01 00:00:00 EDT 2007
Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma.
International journal of cancer
Su PF,Lee TC,Lin PJ,Lee PH,Jeng YM,Chen CH,Liang JD,Chiou LL,Huang GT,Lee HS
MA5-13506 was used in immunohistochemistry to investigate the association of DNA methylation with hepatitis B virus infection
Sat Sep 15 00:00:00 EDT 2007
Effectiveness of interferon-beta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma.
World journal of surgical oncology
Fujimaki T,Ishii H,Matsuno A,Arai H,Nakagomi T
MA5-13506 was used in immunohistochemistry to investigate the efficacy of interferon beta and temozolomide combination therapy on in the treatment of anaplastic astrocytoma
Sat Aug 04 00:00:00 EDT 2007
Protective effect of O6-methylguanine-DNA-methyltransferase on mammalian cells.
Chinese medical journal
Li DB,Wang JS,Fang Q,Sun HY,Xu W,Li WD
MA5-13506 was used in western blot to examine the role of O6-methylguanine-DNA-methyltransferase in DNA repair and cancer cel resistence
Fri Apr 20 00:00:00 EDT 2007
Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions.
Cancer science
Ogawa T,Yoshida T,Tsuruta T,Saigenji K,Okayasu I
MA5-13506 was used in immunohistochemistry to study chromosome 17 genetic instability in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions
Fri Dec 01 00:00:00 EST 2006
Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
The journal of gene medicine
Kramer BA,Lemckert FA,Alexander IE,Gunning PW,McCowage GB
MA5-13506 was used in flow cytometry to study a transgenic mouse line with a specific mutation in O6-methylguanine DNA-methyltransferase
Fri Sep 01 00:00:00 EDT 2006
The prognostic impact of O6-Methylguanine-DNA Methyltransferase (MGMT) promotor hypermethylation in esophageal adenocarcinoma.
International journal of cancer
Baumann S,Keller G,Pühringer F,Napieralski R,Feith M,Langer R,Höfler H,Stein HJ,Sarbia M
MA5-13506 was used in immunohistochemistry to study the prognostic value of MGMT promotor hypermethylation in esophageal adenocarcinoma
Sat Jul 15 00:00:00 EDT 2006
Postchemotherapy characteristics of hepatic colorectal metastases: remnants of uncertain malignant potential.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
Znajda TL,Hayashi S,Horton PJ,Martinie JB,Chaudhury P,Marcus VA,Jass JR,Metrakos P
MA5-13506 was used in immunohistochemistry to study the postchemotherapy characteristics of hepatic colorectal metastases
Sat Apr 01 00:00:00 EST 2006
Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer.
The Journal of molecular diagnostics : JMD
Fox EJ,Leahy DT,Geraghty R,Mulcahy HE,Fennelly D,Hyland JM,O'Donoghue DP,Sheahan K
MA5-13506 was used in ELISA to study the mutually exclusive promoter hypermethylation patterns of hMLH1 and MGMT in colorectal cancer
Wed Feb 01 00:00:00 EST 2006
Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research
Brell M,Tortosa A,Verger E,Gil JM,Viñolas N,Villá S,Acebes JJ,Caral L,Pujol T,Ferrer I,Ribalta T,Graus F
MA5-13506 was used in immunohistochemistry to investigate the association between MGMT expression and chemotherapy prognosis in anaplastic gliomas
Fri Jul 15 00:00:00 EDT 2005
Demographic and pathological characteristics of serrated polyps of colorectum.
Histopathology
Higuchi T,Sugihara K,Jass JR
MA5-13506 was used in immunohistochemistry to investigate the clinicopathological features of serrated polyps of colorectum
Fri Jul 01 00:00:00 EDT 2005
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma.
International journal of cancer
Zhang YJ,Chen Y,Ahsan H,Lunn RM,Lee PH,Chen CJ,Santella RM
MA5-13506 was used in immunohistochemistry to study inactivation of the DNA repair gene MGMT by promoter hypermethylation in hepatocellular carcinoma
Mon Feb 10 00:00:00 EST 2003
Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.
Cancer research
Liu L,Xu-Welliver M,Kanugula S,Pegg AE
MA5-13506 was used in western blot to investigate the effect of nitric oxide on alkylguanine-DNA alkyltransferase
Sat Jun 01 00:00:00 EDT 2002
Degradation of the alkylated form of the DNA repair protein, O(6)-alkylguanine-DNA alkyltransferase.
Carcinogenesis
Xu-Welliver M,Pegg AE
MA5-13506 was used in western blot to study the mechanism of degradation of the alkylated form of the DNA repair protein O(6)-alkylguanine-DNA alkyltransferase
Wed May 01 00:00:00 EDT 2002
Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells.
Leukemia research
Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C
MA5-13506 was used in western blot to investigate the role of MGMT and MDR1 on chemotherapy tolerance
Fri Mar 01 00:00:00 EST 2002
Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA.
The Journal of pharmacology and experimental therapeutics
Zhang Q,Ohannesian DW,Kreklau EL,Erickson LC
MA5-13506 was used in western blot to evaluate the therapeutic efficacy of O6-methylguanine DNA methyltransferase inhibition in cancer chemotherapy
Sun Jul 01 00:00:00 EDT 2001
Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase.
American journal of physiology. Lung cellular and molecular physiology
Wu M,Kelley MR,Hansen WK,Martin WJ
MA5-13506 was used in western blot to investigate the effect of the O6-methylguanine-DNA methyltransferase on the BCNU toxicity to lung cells
Sun Apr 01 00:00:00 EST 2001
