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Product Details
MA5-28816
Product Specifications
Species Reactivity
Avian,
Chicken
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
F21-2
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5 mg/mL
Purification
purified
Storage buffer
PBS, pH 7.4
Contains
<0.1% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745775
Target Information
Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha chain 2; antigen presentation; antigen presentation; BFIV major; BF12 major; B-F antigen; G-B1; B-F histocompatibility F10 antigen; B-F major; B-F minor; B-F-beta-IV; chicken MHC class I antigen; class I histocompatibility antigen, F10 alpha chain; F10 alpha chain; major histocompatibility complex class I glycoprotein; major histocompatibility complex, class I, G; MHC BF2 class I; MHC class I alpha chain 1; MHC class I alpha chain 2; MHC class I antigen alpha chain; MHC class I antigen B-F heavy chain; MHC class I antigen B-F major heavy chain; MHC class I antigen B-F minor heavy chain; MHC class I antigen heavy chain; MHC class I glycoprotein; MHC class I molecule; MHC class1 antigen; minor antigen
Gene Aliases: B-F; B-F-S01; B-F-S02; B-F-S03; B-F-S04; B-F-S05; B-F-S06; B-F-S07; B-F-S09; B-F-S11; B-F-S12; B-F-S13; B-F-S14; B-F1; B-FI; B-FIV; B-LB2; B12; BF; BF12; BF2; BFa1; BFa2; BFIV; BFIV21; BFw-03; BFw-05; BFz-01; HFE
Entrez Gene ID: (Chicken) 693260, (Chicken) 425389
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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