|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human HLA-E denaturated heavy chain.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody reacts with denaturated heavy chain of human HLA-E.
The antibody MEM-E/02 specifically reacts with denaturated heavy chain of human HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of all human cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gastric cancer progression may involve a shift in HLA-E profile from an intact heterodimer to ß2-microglobulin-free monomer.
MA1-19309 was used in flow cytometry and immunohistochemistry to study the potential role of a shift in HLA-E from intact heterodimer to beta-2-macroglobulin-free monomer in the progression of gastric cancer
|Sasaki T,Ravindranath MH,Terasaki PI,Freitas MC,Kawakita S,Jucaud V||International journal of cancer (134:1558)||2014|
Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds.
MA1-19309 was used in immunohistochemistry - paraffin section to optimize rhesus monkey decellularized kidney scaffolds
|Nakayama KH,Lee CC,Batchelder CA,Tarantal AF||PloS one (8:null)||2013|
HLA-E monoclonal antibodies recognize shared peptide sequences on classical HLA class Ia: relevance to human natural HLA antibodies.
MA1-19309 was used in ELISA to study the cross-reaction of some of the natural HHLA-E antibodies with HLA-Ia alleles
|Ravindranath MH,Taniguchi M,Chen CW,Ozawa M,Kaneku H,El-Awar N,Cai J,Terasaki PI||Molecular immunology (47:1121)||2010|