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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||human MICA and MICB proteins|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
HLA class I antigen; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; MICA; MICB; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A
MIC-A; MICA; MICB; PERB11.1; PERB11.2