The antibody detects endogenous levels of total MIG7 protein.
MIG7 is a cysteine-rich protein found in cell membranes and cytoplasm of carcinoma cells. Tumor tissue and blood from over 200 cancer patients have been shown to express MIG7, regardless of tissue origin. In contrast, it has not been detectable in tissues or blood from normal subjects. Expression of MIG7 seems to be restricted to carcinoma cells and putatively to the early placenta (Cytotrophoblast) and it's expression is important for the invasive capabilities of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Entrez Gene ID: (Human) 723788