|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 42 and 191 of Human MITF|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29826 targets MITF in WB applications and shows reactivity with Human samples.
The PA5-29826 immunogen is recombinant protein fragment corresponding to a region within amino acids 42 and 191 of Human MITF.
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHe32; Class E basic helix-loop-helix protein 32; MI; microphtalmia-associated transcription factor; Microphthalmia-associated transcription factor; WS2; WS2A
Gene Aliases: BHLHE32; CMM8; MI; MITF; WS2; WS2A
UniProt ID: (Human) O75030
Entrez Gene ID: (Human) 4286
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