MA5-14233 targets MMP-10 (Stromelysin-2) in IP and WB applications and shows reactivity with Human samples.
The MA5-14233 immunogen is human recombinant MMP-10 (stromelysin-2 protein).
MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
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Protein Aliases: matrix metallo protease; matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP; MMP-10; MMPs; SL-2; stromelysin 2; Stromelysin-2; transin 2; Transin-2
Gene Aliases: MMP10; SL-2; STMY2
UniProt ID: (Human) P09238
Entrez Gene ID: (Human) 4319