|Immunoprecipitation (IP)||2 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
|Immunohistochemistry (IHC)||See 4 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Human recombinant MMP-10 (stromelysin-2 protein)|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14233 targets MMP-10 (Stromelysin-2) in IP and WB applications and shows reactivity with Human samples.
The MA5-14233 immunogen is human recombinant MMP-10 (stromelysin-2 protein).
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading extracellular matrix. Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The two forms of stromelysin (SL), types 1 (MMP-3) and 2 (MMP-10), share 82% sequence homology, but exhibit differences in cellular synthesis and inducibility by cytokines and growth factors in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP-10; SL-2; stromelysin 2; Stromelysin-2; transin 2; Transin-2
Gene Aliases: MMP10; SL-2; STMY2
UniProt ID: (Human) P09238
Entrez Gene ID: (Human) 4319
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