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MMP11 Antibody (MA5-35067) in WB
Western blot analysis of MMP11 in extracts of various cell lines. Samples were incubated with MMP11 Monoclonal antibody (Product # MA5-35067) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
MA5-35067
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC0523
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 389-488 of human MMP11 (P24347)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848972
Product Specific Information
Immunogen sequence: AALVWGPEKN KIYFFRGRDY WRFHPSTRRV DSPVPRRATD WRGVPSEIDA AFQDADGYAY FLRGRLYWKF DPVKVKALEG FPRLVGPDFF GCAEPANTFL
Target Information
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: matrix metallo protease; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11 (stromelysin 3); Matrix metalloproteinase-11; MMP; MMP-11; MMPs; SL-3; stromelysin III; Stromelysin-3
Gene Aliases: MMP-11; MMP11; SL-3; ST3; STMY3
UniProt ID: (Human) P24347, (Mouse) Q02853, (Rat) Q499S5
Entrez Gene ID: (Human) 4320, (Mouse) 17385, (Rat) 25481
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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