Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Matrix metallopeptidase 16 during embryonic development, reproduction, and tissue remodeling. MMP-16 is also involved in the ECM degradation processes associated with arthritis and metastasis. In humans, MMP-16 is a part of a cluster of MMP genes at the 11q22.3 locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp761D112; matrix metallo protease; matrix metallopeptidase 16 (membrane-inserted); matrix metalloproteinase 16; Matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP; MMP-16; MMP-X2; MMPs; MT-MMP 3; MT3-MMP; MT3MMP; MTMMP3; Putative transmembrane protein C8orf57
Gene Aliases: C8orf57; MMP-X2; MMP16; MMPX2; MT-MMP2; MT-MMP3; MT3-MMP