|Immunofluorescence (IF)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Immunohistochemistry (IHC)||See 2 publications below|
|Tested Species reactivity||Cat, Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Rat Mouse|
|Host / Isotype||Mouse / IgM|
|Immunogen||Glial membrane proteins followed by rat CNS white matter.|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C, do not freeze|
MA1-21809 detects MOSP in Human, Rat, Mouse, Feline and Non-human primate samples.
MA1-21809 has been successfully used in Immunofluorescence and Immunohistochemistry (Frozen) procedures.
MA1-21809 immunogen corresponds to Glial membrane proteins followed by rat CNS white matter..
Myelin / Oligodendrocyte Specific Protein (MOSP) (pI of ~6.7) is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On demyelination, immunoreactivity for MOSP, like MBP, is lost.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DUSP25; dystonia 2, torsion (autosomal recessive); FLJ20442; MOG alpha-5; MOG AluA; MOG AluB; MOG Ig-AluB; MOSP; Myelin-oligodendrocyte glycoprotein; RP11-190A12.1; VHZ
Gene Aliases: B230317G11Rik; BTN6; BTNL11; MOG; MOGIG2; NRCLP7
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