This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.
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Protein Aliases: discs; Discs large homolog 3; discs, large homolog 3; DLG3; large homolog 3; MAGUK p55 subfamily member 3; membrane protein palmitoylated 3; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3); Protein MPP3
Gene Aliases: DLG3; MPP3
UniProt ID: (Human) Q13368
Entrez Gene ID: (Human) 4356