Immunogen sequence: SDSRTHSLRY FRLGVSDPIH GVPEFISVGY VDSHPITTYD SVTRQKEPRA PWMAENLAPD HWERYTQLLR GWQQMFKVEL KRLQRHYNHS DNVAHTIKQA WEANQHELLY QKNWLEEECI AWLKRFLEYG KDTLQRTEPP LVRVNRKETF PGVTALFCKA HGFYPPEIYM TWMKNGEEIV QEIDYGDILP SGDGTYQAWA SIELDPQSSN LYSCHVEHCG VHMVLQVPQE SETIPLVMKA V; Positive Samples: Mouse skeletal muscle; Cellular Location: Cell membrane, Endoplasmic reticulum, Endoplasmic reticulum membrane, Extracellular side, Single-pass membrane protein, Single-pass type I membrane protein
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Class I histocompatibility antigen-like protein; histocompatibility-2 complex class 1-like sequence; Major histocompatibility complex class I-related gene protein; MCH class I; MHC class I-related gene protein; MHC class-I related-gene protein
Gene Aliases: H2ls; Mr1; Mr1a
UniProt ID: (Mouse) Q8HWB0
Entrez Gene ID: (Mouse) 15064