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Product Details
PA5-63988
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MRCK gamma. Recombinant protein control fragment (Product #RP-103424).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644100
Product Specific Information
Immunogen sequence: SNDIFQVGEC RRVQQLTLSP SAGLLVVLCG RGPSVRLFAL AELENIEVAG AKIPESRGCQ VLAAGSILQA RTPVLCV
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.
Target Information
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC42 binding protein kinase gamma (DMPK-like); CDC42-binding protein kinase gamma; CDC42BPG; DMPK-like gamma; MRCK gamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase like protein; Myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; Serine/threonine-protein kinase MRCK gamma
Gene Aliases: CDC42BPG; DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma
UniProt ID: (Human) Q6DT37
Entrez Gene ID: (Human) 55561
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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