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MGC3207 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, MGC3207 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: M1Pi; Mediator of RhoA-dependent invasion; Methylthioribose-1-phosphate isomerase; methylthioribose-1-phosphate isomerase homolog; MGC3207; MRI1; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; S-methyl-5-thioribose-1-phosphate isomerase 1; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Gene Aliases: MRDI; MRI1; MTNA; UNQ6390/PRO21135; Ypr118w
UniProt ID: (Human) Q9BV20
Entrez Gene ID: (Human) 84245
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