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Invitrogen
MRP4 Monoclonal Antibody (M4I-80)
FIGURE: 1 / 3
MRP4 Antibody (MA1-35682) in WB
Journal of inflammation research 2022 -
Figure 5 Expression of targeted renal proteins and mRNA in NOD/SCID mice treated with S3I-201. ( A ) Expression of target proteins in NOD/SCID mice kidney detected using Western blotting. ( B ) Expression of targeted proteins was quantified and can be seen in the bar graphs. *p < 0.05, ** p < 0.01, versus the control group; # p < 0.05, ## p < 0.01, the ALL-S3I-201 group versus the control group. ( C ) The f... View More
Product Details
MA1-35682
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Published species
Human
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
M4I-80
Immunogen
MRP4 aa 372-431
Conjugate
Form
Liquid
Concentration
200 µg/mL
Storage buffer
tissue culture supernatant with 0.7% BSA
Contains
0.1% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2241992
Product Specific Information
The M4I-80 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431. MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-80 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP-binding cassette sub-family C member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MOAT-B; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; Multidrug resistance-associated protein 4; RP11-74A12.1
Gene Aliases: ABCC4; D630049P08Rik; MOAT-B; MOATB; MRP4
UniProt ID: (Human) O15439, (Mouse) E9Q236
Entrez Gene ID: (Human) 10257, (Mouse) 239273
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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