|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Bacterial fusion protein of human MRP 6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein|
|Storage buffer||tissue culture supernatant with 1% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:20-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20-1:50|
|Western Blot (WB)||1:20-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-26542 detects MRP6 from human samples.
MA1-26542 has been successfully used in immunohistochemistry (paraffin and frozen), immunocytochemistry and Western blot procedures.
The MA1-26542 immunogen is a bacterial fusion protein of human MRP 6, containing residues 764-964. This sequence spans the putative 12th transmembrane region and pedicted internal and external regions of the protein.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.