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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3).
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Protein Aliases: 28S ribosomal protein S27, mitochondrial; mitochondrial 28S ribosomal protein S27; Mitochondrial ribosomal protein S27; Mitochondrial small ribosomal subunit protein mS27; MRP-S27
Gene Aliases: KIAA0264; MRP-S27; MRPS27; S27mt
UniProt ID: (Human) Q92552
Entrez Gene ID: (Human) 23107
Molecular Function:
RNA binding protein
nucleic acid binding
ribosomal protein
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