Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternate splice variants of this gene have been described but their full-length nature has not been determined.
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Protein Aliases: 28S ribosomal protein S34, mitochondrial; mitochondrial 28S ribosomal protein S34; Mitochondrial small ribosomal subunit protein mS34; MRP-S34; rt34; S34mt
Gene Aliases: MRP-S12; MRP-S34; MRPS12; MRPS34
UniProt ID: (Human) P82930
Entrez Gene ID: (Human) 65993