Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:200 | - |
Immunocytochemistry (ICC/IF) |
1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
UMAB156 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 38-242 of human MRPS7 produced in E.coli. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
0.5-1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 28S ribosomal protein S7, mitochondrial; 30S ribosomal protein S7 homolog; bMRP-27a; bMRP27a; Mitochondrial small ribosomal subunit protein uS7m; MRP-S7
Gene Aliases: bMRP27a; MRP-S; MRP-S7; MRPS7; RP-S7; RPMS7; S7mt
UniProt ID: (Human) Q9Y2R9
Entrez Gene ID: (Human) 51081
Molecular Function:
ribosomal protein
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